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Acute Kidney Injury is a serious medical condition which affects lakhs of people. Most cases of Acute Kidney Injury are caused by reduced blood flow to the kidneys, usually in a patient who’s unwell with another medical condition. The reduced blood flow could be caused by severe dehydration from excessive vomiting or diarrhea or low blood volume after bleeding. Patients in intensive care unit (ICU) who develop Acute Kidney Injury have increased morbidity and mortality, prolonged length of stay in ICU and hospital and increased costs, especially when they require renal replacement therapy. Critical Care Nephrology allows physicians to care for patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. Such medical experts are highly qualified and experienced with the latest innovations in renal replacement methods and improved delivery of dialysis to critically ill people. These inventive methods are proving to be successful in improving the outcomes of people with acute renal failure admitted in a critical care set up What are the signs and symptoms of acute kidney injury? Acute Kidney Injury may be subclinical (detected on laboratory testing) or clinical (presenting with symptoms &/or signs). The majority of these symptoms and signs depend on the underlying cause and may include: Change in urine output: too little urine formed (very common) vs excess urine output (uncommon) Swelling in legs, ankles, or around the eyes Poor appetite Generalized weakness, fatigue, or tiredness Shortness of breath Chest pain or discomfort Nausea, vomiting Abdominal pain or discomfort Confusion, seizures, or coma in severe cases